Authors
Karina M Meragelman, Lyndon M West, Peter T Northcote, Lewis K Pannell, Tawnya C McKee, Michael R Boyd
Publication date
2002/9/20
Journal
The Journal of Organic Chemistry
Volume
67
Issue
19
Pages
6671-6677
Publisher
American Chemical Society
Description
Four new indoles, ancorinolates A−C and bis-ancorinolate B, which contain sulfamate and sulfate groups, were isolated from the aqueous extract of the sponge Ancorina sp. In addition, ancorinazole, an indolo[3,2-a]carbazole also possessing sulfamate and sulfate groups, was isolated from two separate New Zealand collections of Ancorina sp. Ancorinazole is the first indolo[3,2-a]carbazole described as a natural product. Ancorinolates A (1) and C (3) showed weak HIV-inhibitory activity in the XTT-based, anticytopathicity assay.
Total citations
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Scholar articles
KM Meragelman, LM West, PT Northcote, LK Pannell… - The Journal of Organic Chemistry, 2002