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A copula-based approach for model bias characterization was previously proposed (18) aiming at improving prediction accuracy compared to other model characterization approaches such as regression and Gaussian Process. This paper proposes an adaptive copula-based approach for model bias identification to enhance the available methodology. The main idea is to use cluster analysis to pre-process data, then apply the copula-based approach using information from each cluster. The final prediction accumulates predictions obtained from each cluster. Two case studies will be used to demonstrate the superiority of the adaptive copula-based approach over its predecessor.