Authors
François Stéphan, Benoit Barrucand, Pascal Petit, Saida Rézaiguia-Delclaux, Anne Médard, Bertrand Delannoy, Bernard Cosserant, Guillaume Flicoteaux, Audrey Imbert, Catherine Pilorge, Laurence Bérard, BiPOP Study Group
Publication date
2015/6/16
Journal
Jama
Volume
313
Issue
23
Pages
2331-2339
Publisher
American Medical Association
Description
Importance
Noninvasive ventilation delivered as bilevel positive airway pressure (BiPAP) is often used to avoid reintubation and improve outcomes of patients with hypoxemia after cardiothoracic surgery. High-flow nasal oxygen therapy is increasingly used to improve oxygenation because of its ease of implementation, tolerance, and clinical effectiveness.
Objective
To determine whether high-flow nasal oxygen therapy was not inferior to BiPAP for preventing or resolving acute respiratory failure after cardiothoracic surgery.
Design and Setting
Multicenter, randomized, noninferiority trial (BiPOP Study) conducted between June 15, 2011, and January 15, 2014, at 6 French intensive care units.
Participants
A total of 830 patients who had undergone cardiothoracic surgery, of which coronary artery bypass, valvular repair, and pulmonary thromboendarterectomy were the most common, were included when they developed …
Scholar articles
F Stéphan, B Barrucand, P Petit, S Rézaiguia-Delclaux… - Jama, 2015