Authors
Dio Kavalieratos, Jennifer Corbelli, DI Zhang, J Nicholas Dionne-Odom, Natalie C Ernecoff, Janel Hanmer, Zachariah P Hoydich, Dara Z Ikejiani, Michele Klein-Fedyshin, Camilla Zimmermann, Sally C Morton, Robert M Arnold, Lucas Heller, Yael Schenker
Publication date
2016/11/22
Source
Jama
Volume
316
Issue
20
Pages
2104-2114
Publisher
American Medical Association
Description
Importance
The use of palliative care programs and the number of trials assessing their effectiveness have increased.
Objective
To determine the association of palliative care with quality of life (QOL), symptom burden, survival, and other outcomes for people with life-limiting illness and for their caregivers.
Data Sources
MEDLINE, EMBASE, CINAHL, and Cochrane CENTRAL to July 2016.
Study Selection
Randomized clinical trials of palliative care interventions in adults with life-limiting illness.
Data Extraction and Synthesis
Two reviewers independently extracted data. Narrative synthesis was conducted for all trials. Quality of life, symptom burden, and survival were analyzed using random-effects meta-analysis, with estimates of QOL translated to units of the Functional Assessment of Chronic Illness Therapy–palliative care scale (FACIT-Pal) instrument (range, 0-184 [worst-best]; minimal clinically important difference …
Scholar articles
D Kavalieratos, J Corbelli, DI Zhang, JN Dionne-Odom… - Jama, 2016