Authors
Gary Rodin, Christopher Lo, Anne Rydall, Joanna Shnall, Carmine Malfitano, Aubrey Chiu, Tania Panday, Sarah Watt, Ekaterina An, Rinat Nissim, Madeline Li, Camilla Zimmermann, Sarah Hales
Publication date
2018/8/10
Journal
Journal of Clinical Oncology
Volume
36
Issue
23
Pages
2422-2432
Publisher
American Society of Clinical Oncology
Description
Purpose
Individuals with advanced cancer experience substantial distress in response to disease burden and impending mortality. Managing Cancer And Living Meaningfully (CALM) is a novel, brief, manualized psychotherapeutic intervention intended to treat and prevent depression and end-of-life distress in patients with advanced cancer. We conducted a randomized controlled trial to compare CALM with usual care (UC) in this population.
Methods
Patients with advanced cancer were recruited from outpatient oncology clinics at a comprehensive cancer center into an unblinded randomized controlled trial. Permuted block randomization stratified by Patient Health Questionnaire-9 depression score allocated participants to CALM plus UC or to UC alone. Assessments of depressive symptoms (primary outcome), death-related distress, and other secondary outcomes were conducted at baseline, 3 months …
Scholar articles
G Rodin, C Lo, A Rydall, J Shnall, C Malfitano, A Chiu… - Journal of Clinical Oncology, 2018
G Rodin, C Lo, A Rydall, R Nissim, C Malfitano… - 2017