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Establishing the normative range of age‐dependent fluorodeoxyglucose (FDG) uptake in the developing brain is necessary for understanding regional quantitative analysis of positron emission tomography (PET) brain images in children and also to provide functional information on brain development. We analyzed head sections of FDG PET/computed tomography (CT) images for 115 patients (5 months to 23 years) without central nervous system disease before treatment, as PET studies are not performed on healthy children owing to ethical considerations and the risk of radiation exposure. We investigated the changes in FDG uptake and established age‐associated normative ranges of cerebral FDG. Head sections of FDG PET/CT images were registered to a population‐based probabilistic atlas of human cortical structures. Gray matter of 56 brain structures was defined on normalized PET images according to …