Authors
Patrick T Delaplain, Jacquelyn L Phillips, Megan Lundeberg, Jeffry Nahmias, Catherine M Kuza, Brian M Sheehan, Linda S Murphy, Marija Pejcinovska, Areg Grigorian, Viktor Gabriel, Philip S Barie, Sebastian D Schubl
Publication date
2020/3/1
Source
Surgical infections
Volume
21
Issue
2
Pages
112-121
Publisher
Mary Ann Liebert, Inc., publishers
Description
Background: We performed a systematic review of the literature on antibiotic prophylaxis practices in open reduction, and internal fixation of, facial fracture(s) (ORIFfx). We hypothesized that prolonged antibiotic prophylaxis (PAP) would not decrease the rate of surgical site infections (SSIs).
Methods: We performed a systematic review of four databases: PubMed, CENTRAL, EMBase, and Web of Science, from inception through January 15, 2017. Three independent reviewers extracted fracture location (orbital, mid-face, mandible), antibiotic use, SSI incidence, and time from injury to surgery. Mantel-Haenszel and generalized estimating equations were carried out independently for each fracture zone.
Results: Of the 587 articles identified, 54 underwent full-text review, yielding 27 studies that met our inclusion criteria. Of these, 16 studies (n = 2,316 patients) provided data for mandible fractures, four studies (n …
Scholar articles
PT Delaplain, JL Phillips, M Lundeberg, J Nahmias… - Surgical infections, 2020