Authors
Andrea V Margulis, Manel Pladevall, Nuria Riera-Guardia, Cristina Varas-Lorenzo, Lorna Hazell, Nancy D Berkman, Meera Viswanathan, Susana Perez-Gutthann
Publication date
2014/10/10
Source
Clinical epidemiology
Pages
359-368
Publisher
Taylor & Francis
Description
Background
The study objective was to compare the Newcastle–Ottawa Scale (NOS) and the RTI item bank (RTI-IB) and estimate interrater agreement using the RTI-IB within a systematic review on the cardiovascular safety of glucose-lowering drugs.
Methods
We tailored both tools and added four questions to the RTI-IB. Two reviewers assessed the quality of the 44 included studies with both tools, (independently for the RTI-IB) and agreed on which responses conveyed low, unclear, or high risk of bias. For each question in the RTI-IB (n=31), the observed interrater agreement was calculated as the percentage of studies given the same bias assessment by both reviewers; chance-adjusted interrater agreement was estimated with the first-order agreement coefficient (AC1) statistic.
Results
The NOS required less tailoring and was easier to use than the RTI-IB, but the RTI-IB produced a more thorough assessment. The …
Scholar articles
AV Margulis, M Pladevall, N Riera-Guardia… - Clinical epidemiology, 2014
AV Margulis, M Pladevall, N Riera-Guardia… - Pharmacoepidemiology and Drug Safety, 2013