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Planning in mining regions needs to accommodate the extraction of minerals/energy resources in co-existence with established land uses, such as agriculture and ecological conservation. Here, we first identify six critical aspects of planning in mining regions: i) the temporal nature of mining operations; ii) spatial dimensions of mining operations; iii) irreversible changes that create post-mining landscapes; iv) social dimensions of mining impacts and corporate responsibility; v) cumulative dimensions of impacts; and vi) a need to integrate methods from a range of disciplines. We then illustrate the potential to address these challenges using integrative modelling nested within a participatory approach to allow for clear, transparent, and stakeholder-inclusive decision-making. We describe a 5-step framework that supports a broadening of strategic assessments and offers mining companies forewarning about potential …