Authors
Natalia Ojeda, Felipe Ortuno, Javier Arbizu, Pilar Lopez, Josep Maria Martí‐Climent, Ivan Penuelas, Salvador Cervera‐Enguix
Publication date
2002/10
Journal
Human brain mapping
Volume
17
Issue
2
Pages
116-130
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Description
Deficits in sustained attention have been frequently described in schizophrenia. The neuroanatomical basis reported previously have included altered levels of activation in cingulate and prefrontal cortex, but the contribution of further regions remains unclear. We explored the full neuroanatomy underlying the sustained attentional deficits observed in naïve schizophrenics compared with controls. Participants included 10 controls and 11 patients. The experimental design included rest, auditory stimulation using clicks, and two counting tasks. Subjects were instructed to mentally count the clicks, and then to count forward at the same frequency they heard previously when listening to the clicks. Relative cerebral blood flow (relCBF) was measured by means of PET 15O‐water. Differences were observed between both groups at superior temporal cortex, superior parietal gyrus, and cerebellum during tasks requiring …
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Scholar articles
N Ojeda, F Ortuno, J Arbizu, P Lopez, JM Martí‐Climent… - Human brain mapping, 2002