Authors
Deniz Oncel, Giulia Corradetti, Ye He, Maryam Ashrafkhorasani, Muneeswar Gupta Nittala, Dwight Stambolian, Margaret A Pericak‐Vance, Jonathan L Haines, Srinivas R Sadda
Publication date
2024/2
Journal
Acta ophthalmologica
Volume
102
Issue
1
Pages
e126-e132
Description
Purpose
This study aimed to investigate the correspondence between intraretinal hyperreflective foci (IHRF) identified on optical coherence tomography (OCT) B‐scans with hyperpigmentation on colour fundus photography (CFP) or hyperreflectivity on infrared reflectance (IR) images in eyes with age‐related macular degeneration (AMD).
Methods
Flash CFP, IR images and OCT B‐scans obtained at the same visit were evaluated. Individual IHRF identified on OCT B‐scans were assessed for the qualitative presence or absence of a hypotransmission tail into the choroid. The corresponding IR image obtained at the time of OCT acquisition was analysed for the presence or absence of hyperreflectivity in this region. The IR images were manually registered to the CFP image, and CFP images were inspected for the presence or absence of hyperpigmentation at the location of IHRF.
Results
From 122 eyes, a total of …
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