Authors
Abdelouahid Tajar, Gianni Forti, Terence W O'Neill, David M Lee, Alan J Silman, Joseph D Finn, György Bartfai, Steven Boonen, Felipe F Casanueva, Aleksander Giwercman, Thang S Han, Krzysztof Kula, Fernand Labrie, Michael EJ Lean, Neil Pendleton, Margus Punab, Dirk Vanderschueren, Ilpo T Huhtaniemi, Frederick CW Wu, EMAS Group
Publication date
2010/4/1
Journal
The Journal of Clinical Endocrinology & Metabolism
Volume
95
Issue
4
Pages
1810-1818
Publisher
Oxford University Press
Description
Context: The diagnosis of late-onset hypogonadism (LOH) in older men with age-related declines in testosterone (T) is currently not well characterized.
Objective: Our objective was to investigate whether different forms of hypogonadism can be distinguished among aging men.
Design: The study was a cross-sectional survey on 3369 community-dwelling men aged 40–79 yr in eight European centers.
Methods: Four groups of subjects were defined: eugonadal (normal T and normal LH), secondary (low T and low/normal LH), primary (low T and elevated LH), and compensated (normal T and elevated LH) hypogonadism. Relationships between the defined gonadal status with potential risk factors and clinical symptoms were investigated by multilevel regression models.
Results: Among the men, 11.8, 2.0, and 9.5% were classified into the secondary, primary, and …
Total citations
Scholar articles
A Tajar, G Forti, TW O'Neill, DM Lee, AJ Silman… - The Journal of Clinical Endocrinology & Metabolism, 2010