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We previously reported improved Asthma Control Questionnaire (ACQ6) and Asthma Quality of Life Questionnaire (AQLQ) scores with weight-loss after 16 weeks of the Counterweight-Plus weight management programme (CWP) compared to usual care (UC) in a single-centre, randomised, controlled trial in patients with difficult-to-treat asthma and obesity.¹ Here we report one-year asthma outcomes from this trial.

We randomised (1:1 CWP:UC) adults with difficult-to-treat asthma and body mass index (BMI) ≥30 kg/m². CWP with dietitian support: 12-week total diet replacement phase (850kcal/day low-energy formula); stepwise food reintroduction and weight loss maintenance up to week 52. Study visits occurred at baseline, 16-weeks and 52-weeks. Outcomes measured include ACQ6, AQLQ and healthcare usage. Minimal clinically important difference (MCID) in ACQ6 is –0.5 and in AQLQ 0.5 …