ผู้เขียน
Neelesh K Nema, Niladri Maity, B Sarkar, Pulok K Mukherjee
วันที่เผยแพร่
2011/5
วารสารวิชาการ
Archives of dermatological research
เล่มที่
303
หน้า
247-252
ผู้เผยแพร่
Springer-Verlag
คำอธิบาย
The aim of this study was to screen the antioxidant, anti-hyaluronidase, and anti-elastase activity of the lyophilized juice of Cucumis sativus fruit (CSLJ). The CSLJ was subjected to DPPH and superoxide radical scavenging assay in reference to butylated hydroxytoluene. The hyaluronidase and elastase inhibitory assay was performed in reference to oleanolic acid. Furthermore, the activities have been rationalized with HPLC analysis of the CSLJ with standard reference compound of ascorbic acid. The CSLJ exhibited DPPH-free radical and superoxide radical scavenging activity, IC50 at a concentration of 14.73 ± 1.42 and 35.29 ± 1.30 μg/mL, respectively. The CSLJ also showed strong anti-hyaluronidase (c P < 0.001) and anti-elastase (c P < 0.001) activity, IC50 at a concentration of 20.98 ± 1.78 and 6.14 ± 1.74 μg/mL, respectively. The HPLC ‘chromatogram’ of standard and …
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