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The past decade has witnessed the development of a new stream of research, one focused on information systems (IS) and their relation to company strategy and the attainment of competitive advantage. A growing number of IS researchers are turning their attention to investigating questions in the IS/business strategy area. This article is intended to provide an overview of business strategy research findings and recommendations that are especially relevant to IS researchers, focusing on key conceptual and measurement issues in three areas: competitive strategy; strategic fit; and business performance. It may be used as a ‘primer’ for IS researchers considering conducting research with business strategy as a reference discipline. It also should be of interest to IS academics generally, inasmuch as the relationship between IS and business strategy has become a key issue in this field.