Authors
GJ Williams, T Quinn, S Lo, P Guitera, RA Scolyer, JF Thompson, S Ch'ng
Publication date
2024/6/6
Source
Journal of the European Academy of Dermatology and Venereology
Description
Background
The use of Mohs micrographic surgery (MMS) in melanoma treatment has divided opinion and evidence‐based guidelines are lacking.
Objectives
This systematic review aimed to analyse clinical outcomes for patients with invasive melanomas treated with Mohs rather than wide local excision (WLE).
Methods
Embase, MEDLINE and Cochrane databases (to 30 August 2023) were searched for studies using Mohs to treat invasive melanoma. Outcomes of interest were local recurrence and death from melanoma.
Results
Thirty‐five articles involving 41,499 patients with invasive melanoma treated with Mohs were identified. Sixteen studies compared Mohs with WLE and 19 were Mohs‐only, non‐comparative studies. Patients treated with Mohs differed significantly from those undergoing WLE, in particular Mohs patients were older and had thinner melanomas. Two comparative studies using the same …
Scholar articles
GJ Williams, T Quinn, S Lo, P Guitera, RA Scolyer… - Journal of the European Academy of Dermatology and …, 2024