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Research on hedonic and eudaimonic orientations has previously focused on their effects on well-being experiences. Very little is known about their associations with functioning. A preliminary objective of the study was to establish the factorial validity of the Hedonic and Eudaimonic Motives for Activities–Revised (HEMA-R) on an Italian sample (N = 461) through a confirmatory factor analysis. The main objective was to study the distinctive patterns of correlates between different types of orientations to well-being and several outcome measures of positive experiences (flourishing, life satisfaction, positive affect), negative experiences (negative affect, depression, anxiety, stress) and functioning (dispositional coping strategies) by means of a multivariate linear model. The Italian version of the HEMA-R showed a three-factor structure, namely eudaimonic, pleasure, and relaxation orientations. Pleasure …