Authors
Parastu Kasaie, Stephen A Berry, Maunank S Shah, Eli S Rosenberg, Karen W Hoover, Thomas L Gift, Harrell Chesson, Jeff Pennington, Danielle German, Colin P Flynn, Chris Beyrer, David W Dowdy
Publication date
2018/12/1
Journal
Sexually transmitted diseases
Volume
45
Issue
12
Pages
791-797
Publisher
LWW
Description
Background
Preexposure prophylaxis (PrEP) greatly reduces the risk of human immunodeficiency virus (HIV) acquisition, but its optimal delivery strategy remains uncertain. Clinics for sexually transmitted infections (STIs) can provide an efficient venue for PrEP delivery.
Methods
To quantify the added value of STI clinic–based PrEP delivery, we used an agent-based simulation of HIV transmission among men who have sex with men (MSM). We simulated the impact of PrEP delivery through STI clinics compared with PrEP delivery in other community-based settings. Our primary outcome was the projected 20-year reduction in HIV incidence among MSM.
Results
Assuming PrEP uptake and adherence of 60% each, evaluating STI clinic attendees and delivering PrEP to eligible MSM reduced HIV incidence by 16%[95% uncertainty range, 14%–18%] over 20 years, an impact that was 1.8 (1.7–2.0) times as great as that …
Scholar articles
P Kasaie, SA Berry, MS Shah, ES Rosenberg… - Sexually transmitted diseases, 2018