Authors
Jessie K Edwards, Stephen R Cole, Tiffany L Breger, Lindsey M Filiatreau, Lauren Zalla, Grace E Mulholland, Michael A Horberg, Michael J Silverberg, M John Gill, Peter F Rebeiro, Jennifer E Thorne, Parastu Kasaie, Vincent C Marconi, Timothy R Sterling, Keri N Althoff, Richard D Moore, Joseph J Eron
Publication date
2022/9/1
Journal
Clinical Infectious Diseases
Volume
75
Issue
5
Pages
867-874
Publisher
Oxford University Press
Description
Background
Mortality among adults with human immunodeficiency virus (HIV) remains elevated over those in the US general population, even in the years after entry into HIV care. We explore whether the elevation in 5-year mortality would have persisted if all adults with HIV had initiated antiretroviral therapy within 3 months of entering care.
Methods
Among 82 766 adults entering HIV care at North American AIDS Cohort Collaboration clinical sites in the United States, we computed mortality over 5 years since entry into HIV care under observed treatment patterns. We then used inverse probability weights to estimate mortality under universal early treatment. To compare mortality with those for similar individuals in the general population, we used National Center for Health Statistics data to construct a cohort representing the subset of the US population matched to study …
Total citations
Scholar articles
JK Edwards, SR Cole, TL Breger, LM Filiatreau, L Zalla… - Clinical Infectious Diseases, 2022