Authors
Kevin D Hall, Alexis Ayuketah, Robert Brychta, Hongyi Cai, Thomas Cassimatis, Kong Y Chen, Stephanie T Chung, Elise Costa, Amber Courville, Valerie Darcey, Laura A Fletcher, Ciaran G Forde, Ahmed M Gharib, Juen Guo, Rebecca Howard, Paule V Joseph, Suzanne McGehee, Ronald Ouwerkerk, Klaudia Raisinger, Irene Rozga, Michael Stagliano, Mary Walter, Peter J Walter, Shanna Yang, Megan Zhou
Publication date
2019/7/2
Journal
Cell metabolism
Volume
30
Issue
1
Pages
67-77. e3
Publisher
Elsevier
Description
We investigated whether ultra-processed foods affect energy intake in 20 weight-stable adults, aged (mean ± SE) 31.2 ± 1.6 years and BMI = 27 ± 1.5 kg/m2. Subjects were admitted to the NIH Clinical Center and randomized to receive either ultra-processed or unprocessed diets for 2 weeks immediately followed by the alternate diet for 2 weeks. Meals were designed to be matched for presented calories, energy density, macronutrients, sugar, sodium, and fiber. Subjects were instructed to consume as much or as little as desired. Energy intake was greater during the ultra-processed diet (508 ± 106 kcal/day; p = 0.0001), with increased consumption of carbohydrate (280 ± 54 kcal/day; p < 0.0001) and fat (230 ± 53 kcal/day; p = 0.0004), but not protein (−2 ± 12 kcal/day; p = 0.85). Weight changes were highly correlated with energy intake (r = 0.8, p < 0.0001), with participants gaining 0.9 ± 0.3 kg (p = 0.009) during the …
Scholar articles
KD Hall, A Ayuketah, R Brychta, H Cai, T Cassimatis… - Cell metabolism, 2019