Authors
Francesco Lescai, Andrea Maria Chiamenti, Alessandra Codemo, Chiara Pirazzini, Giuseppe D'Agostino, Cristina Ruaro, Roberta Ghidoni, Luisa Benussi, Daniela Galimberti, Federica Esposito, Francesca Marchegiani, Maurizio Cardelli, Fabiola Olivieri, Benedetta Nacmias, Sandro Sorbi, Fabrizio Tagliavini, Diego Albani, Filippo Martinelli Boneschi, Giuliano Binetti, Aurelia Santoro, Gianluigi Forloni, Elio Scarpini, Gaetano Crepaldi, Carlo Gabelli, Claudio Franceschi
Publication date
2011/1/1
Journal
Journal of Alzheimer's Disease
Volume
24
Issue
2
Pages
235-245
Publisher
IOS Press
Description
This paper addresses a tenet of the literature on APOE, ie, the relationship between the effects of the 4, one of the established genetic risk factor for Alzheimer’s disease (AD), and its expression levels as determined by APOE promoter polymorphisms. Five polymorphisms (− 491 rs449647,− 427 rs769446,− 219 rs405509, and rs429358–rs7412) were studied in 1308 AD patients and 1082 control individuals from the Central-Northern Italy. Major findings of the present study are the
Scholar articles
F Lescai, AM Chiamenti, A Codemo, C Pirazzini… - Journal of Alzheimer's Disease, 2011