Authors
Felipe Fregni, Paulo S Boggio, Marcelo C Santos, Moises Lima, Adriana L Vieira, Sergio P Rigonatti, M Teresa A Silva, Egberto R Barbosa, Michael A Nitsche, Alvaro Pascual‐Leone
Publication date
2006/10
Journal
Movement disorders
Volume
21
Issue
10
Pages
1693-1702
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Description
Electrical stimulation of deep brain structures, such as globus pallidus and subthalamic nucleus, is widely accepted as a therapeutic tool for patients with Parkinson's disease (PD). Cortical stimulation either with epidural implanted electrodes or repetitive transcranial magnetic stimulation can be associated with motor function enhancement in PD. We aimed to study the effects of another noninvasive technique of cortical brain stimulation, transcranial direct current stimulation (tDCS), on motor function and motor‐evoked potential (MEP) characteristics of PD patients. We tested tDCS using different electrode montages [anodal stimulation of primary motor cortex (M1), cathodal stimulation of M1, anodal stimulation of dorsolateral prefrontal cortex (DLPFC), and sham‐stimulation] and evaluated the effects on motor function—as indexed by Unified Parkinson's Disease Rating Scale (UPDRS), simple reaction time (sRT …
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