Authors
SM Slobounov, Michael Gay, Kai Zhang, Brian Johnson, D Pennell, Wayne Sebastianelli, S Horovitz, Mark Hallett
Publication date
2011/4/15
Journal
Neuroimage
Volume
55
Issue
4
Pages
1716-1727
Publisher
Academic Press
Description
There is still controversy in the literature whether a single episode of mild traumatic brain injury (mTBI) results in short- and/or long-term functional and structural deficits in the concussed brain. With the inability of traditional brain imaging techniques to properly assess the severity of brain damage induced by a concussive blow, there is hope that more advanced applications such as resting state functional magnetic resonance imaging (rsFMRI) will be more specific in accurately diagnosing mTBI. In this rsFMRI study, we examined 17 subjects 10±2days post-sports-related mTBI and 17 age-matched normal volunteers (NVs) to investigate the possibility that the integrity of the resting state brain network is disrupted following a single concussive blow. We hypothesized that advanced brain imaging techniques may reveal subtle alterations of functional brain connections in asymptomatic mTBI subjects. There are several …
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