Authors
Douglas T Hess, Akio Matsumoto, Sung-Oog Kim, Harvey E Marshall, Jonathan S Stamler
Publication date
2005/2/1
Source
Nature reviews Molecular cell biology
Volume
6
Issue
2
Pages
150-166
Publisher
Nature Publishing Group UK
Description
S-nitrosylation, the covalent attachment of a nitrogen monoxide group to the thiol side chain of cysteine, has emerged as an important mechanism for dynamic, post-translational regulation of most or all main classes of protein. S-nitrosylation thereby conveys a large part of the ubiquitous influence of nitric oxide (NO) on cellular signal transduction, and provides a mechanism for redox-based physiological regulation.
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Scholar articles
DT Hess, A Matsumoto, SO Kim, HE Marshall… - Nature reviews Molecular cell biology, 2005