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Multiple myeloma is a plasma cell disorder that constitutes 10% of all haematopoietc neoplasias. Although it is a systemic disorder affecting various organs involving bones and kidneys, skin involvement is a rare finding which has never been reported in Korea. Recently, we experienced a case of multiple myeloma recurring as a single lesion of erythematous nodular rash and herein we report this case with brief review of literatures.(Korean J Med 70: 711-714, 2006) Key Words: Multiple myeloma, Skin manifestations