Authors
Joachim Ostermann, Arthur L Horwich, Walter Neupert, F-Ulrich Hartl
Publication date
1989/9/14
Journal
Nature
Volume
341
Issue
6238
Pages
125-130
Publisher
Nature Publishing Group UK
Description
Mitochondrial heat-shock protein hsp60 functions in the folding of proteins imported into mitochon-dria. Folding occurs at the surface of hsp60 in an ATP-mediated reaction, followed by release of the bound polypeptides. We propose that hsp60 catalyses protein folding.
Total citations
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