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We present an interpretation of the eastern half portion of the CROP 11 line, a deep reflection seismic profile 265 km long that cuts across the central Apennines from the Tyrrhenian coast to the Adriatic coast. In the study area the line cuts across a pile of thrust sheets that underwent tectonic transport between the Messinian and the Pleistocene. In its easternmost part, the line runs through the Plio‐Pleistocene deposits of the Adriatic foredeep. In the foreland region the CROP 11 line integrates previous information on the crustal structure derived from petroleum exploration and from deep seismic sounding refraction experiments. In particular, the CROP 11 line confirms the existence of a very thick sedimentary sequence underlying the Mesozoic‐Tertiary carbonates of the Apulia Platform interpreted as the Paleozoic‐Triassic sedimentary cover of a pre‐Cambrian crystalline basement. In the mountain chain, where the …