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In the era of “big data”, recent developments in the area of information and communication technologies (ICT) are facilitating organizations to innovate and grow. These technological developments and wide adaptation of ubiquitous computing enable numerous opportunities for government and companies to reconsider healthcare prospects. Therefore, big data and smart healthcare systems are independently attracting extensive attention from both academia and industry. The combination of both big data and smart systems can expedite the prospects of the healthcare industry. However, a thorough study of big data and smart systems together in the healthcare context is still absent from the existing literature. The key contributions of this article include an organized evaluation of various big data and smart system technologies and a critical analysis of the state-of-the-art advanced healthcare systems. We describe …