Authors
Gillian Elizabeth Caughey, Emmae N Ramsay, Agnes I Vitry, Andrew L Gilbert, Mary A Luszcz, Philip Ryan, Elizabeth E Roughead
Publication date
2010/12/1
Journal
Journal of Epidemiology & Community Health
Volume
64
Issue
12
Pages
1036-1042
Publisher
BMJ Publishing Group Ltd
Description
Objectives
To determine the impact of comorbid chronic diseases on mortality in older people.
Design
Prospective cohort study (1992–2006). Associations between numbers of chronic diseases or mutually exclusive comorbid chronic diseases on mortality over 14 years, by Cox proportional hazards model adjusting for sociodemographic variables or Kaplan–Meier analyses, respectively.
Setting
Population based, Australia.
Participants
2087 randomly selected participants aged ≥65 years old, living in the community or institutions.
Main results
Participants with 3–4 or ≥5 diseases had a 25% (95% CI 1.05 to 1.5, p=0.01) and 80% (95% CI 1.5 to 2.2, p<0.0001) increased risk of mortality, respectively, by comparison with no chronic disease, after adjusting for age, sex and residential status. When cardiovascular disease (CVD), mental health problem or diabetes were comorbid with arthritis, there was a trend towards …
Total citations
Scholar articles
GE Caughey, EN Ramsay, AI Vitry, AL Gilbert… - Journal of Epidemiology & Community Health, 2010