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The study of rock-uplift variations in time and space can provide insights into the processes driving the topographic evolution of mountain belts. The Apennine mountain chain of Italy, one of the more recently developed mountain belts in the Mediterranean region, has undergone a strong Quaternary rock-uplift phase, particularly in the north-central sector, which has shaped the present-day topography. It has long been recognized that drainage systems can record temporal and spatial variations in rock-uplift rates. Specifically, in detachment-limited systems with simple settings (eg, no significant variations in drainage area over time, and catchments mostly draining perpendicular to regional structures), river profiles can be inverted to reconstruct their history of rock uplift. In this study, we present linear inversions of river profiles from 28 catchments along the eastern flank of the northern-central Apennines. These …