Authors
Anuradhaa Subramanian, Krishnarajah Nirantharakumar, Sarah Hughes, Puja Myles, Tim Williams, Krishna M Gokhale, Tom Taverner, Joht Singh Chandan, Kirsty Brown, Nikita Simms-Williams, Anoop D Shah, Megha Singh, Farah Kidy, Kelvin Okoth, Richard Hotham, Nasir Bashir, Neil Cockburn, Siang Ing Lee, Grace M Turner, Georgios V Gkoutos, Olalekan Lee Aiyegbusi, Christel McMullan, Alastair K Denniston, Elizabeth Sapey, Janet M Lord, David C Wraith, Edward Leggett, Clare Iles, Tom Marshall, Malcolm J Price, Steven Marwaha, Elin Haf Davies, Louise J Jackson, Karen L Matthews, Jenny Camaradou, Melanie Calvert, Shamil Haroon
Publication date
2022/8
Journal
Nature medicine
Volume
28
Issue
8
Pages
1706-1714
Publisher
Nature Publishing Group
Description
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is associated with a range of persistent symptoms impacting everyday functioning, known as post-COVID-19 condition or long COVID. We undertook a retrospective matched cohort study using a UK-based primary care database, Clinical Practice Research Datalink Aurum, to determine symptoms that are associated with confirmed SARS-CoV-2 infection beyond 12 weeks in non-hospitalized adults and the risk factors associated with developing persistent symptoms. We selected 486,149 adults with confirmed SARS-CoV-2 infection and 1,944,580 propensity score-matched adults with no recorded evidence of SARS-CoV-2 infection. Outcomes included 115 individual symptoms, as well as long COVID, defined as a composite outcome of 33 symptoms by the World Health Organization clinical case definition. Cox proportional hazards models …
Total citations
Scholar articles
A Subramanian, K Nirantharakumar, S Hughes… - Nature medicine, 2022