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In this paper, a modified cubic B-spline differential quadrature method (MCB-DQM) is employed for the numerical simulation of two-space dimensional nonlinear sine-Gordon equation with appropriate initial and boundary conditions. The modified cubic B-spline works as a basis function in the differential quadrature method to compute the weighting coefficients. Accordingly, two dimensional sine-Gordon equation is transformed into a system of second order ordinary differential equations (ODEs). The resultant system of ODEs is solved by employing an optimal five stage and fourth-order strong stability preserving Runge–Kutta scheme (SSP-RK54). Numerical simulation is discussed for both damped and undamped cases. Computational results are found to be in good agreement with the exact solution and other numerical results available in the literature.