Authors
Katrin Kierdorf, Marco Prinz, Frederic Geissmann, Elisa Gomez Perdiguero
Publication date
2015/12/1
Source
Seminars in immunology
Volume
27
Issue
6
Pages
369-378
Publisher
Academic Press
Description
Macrophages are important for tissue development, homeostasis as well as immune response upon injury or infection. For a long time they were only seen as one uniform group of phagocytes with a common origin and similar functions. However, this view has been challenged in the last decade and revealed a complex diversity of tissue resident macrophages. Here, we want to present the current view on macrophage development and tissue specification and we will discuss differences as well as common patterns between heterogeneous macrophage subpopulations.
Scholar articles
K Kierdorf, M Prinz, F Geissmann, EG Perdiguero - Seminars in immunology, 2015