Authors
Yoshimi Anzai, Catherine W Piccoli, Eric K Outwater, William Stanford, David A Bluemke, Pamela Nurenberg, Sanjay Saini, Kenneth R Maravilla, David E Feldman, Udo P Schmiedl, James A Brunberg, Isaac R Francis, Steven E Harms, Peter M Som, Clare M Tempany
Publication date
2003/9
Journal
Radiology
Volume
228
Issue
3
Pages
777-788
Publisher
Radiological Society of North America
Description
PURPOSE: To determine the safety and efficacy of ferumoxtran 10–enhanced magnetic resonance (MR) imaging for diagnosis of metastases to lymph nodes and the clinical usefulness of ferumoxtran 10 in nodal staging.
MATERIALS AND METHODS: One hundred fifty-two patients were injected with ferumoxtran 10. Readers independently evaluated precontrast MR images by using node size criteria and subjective assessment of other imaging features. Ferumoxtran 10–enhanced MR images were evaluated alone and paired with precontrast images for comparison. The diagnostic performances of precontrast MR size criteria and postcontrast MR imaging were evaluated with receiver operating characteristic (ROC) analysis. Lymph node signal intensity was correlated with histopathologic findings. MR imaging and histopathologic nodal stages were compared.
RESULTS: Node-level sensitivity, specificity …
Total citations
Scholar articles
Y Anzai, CW Piccoli, EK Outwater, W Stanford… - Radiology, 2003