Authors
Perminder S Sachdev, Henry Brodaty, Simone Reppermund, Nicole A Kochan, Julian N Trollor, Brian Draper, Melissa J Slavin, John Crawford, Kristan Kang, G Anthony Broe, Karen A Mather, Ora Lux, Memory and Ageing Study Team
Publication date
2010/12
Journal
International psychogeriatrics
Volume
22
Issue
8
Pages
1248-1264
Publisher
Cambridge University Press
Description
Background
The Sydney Memory and Ageing Study (Sydney MAS) was initiated in 2005 to examine the clinical characteristics and prevalence of mild cognitive impairment (MCI) and related syndromes, and to determine the rate of change in cognitive function over time.
Methods
Non-demented community-dwelling individuals (N = 1037) aged 70–90 were recruited from two areas of Sydney, following a random approach to 8914 individuals on the electoral roll. They underwent detailed neuropsychiatric and medical assessments and donated a blood sample for clinical chemistry, proteomics and genomics. A knowledgeable informant was also interviewed. Structural MRI scans were performed on 554 individuals, and subgroups participated in studies of falls and balance, metabolic and inflammatory markers, functional MRI and prospective memory. The cohort is to be followed up with brief telephone reviews annually …
Total citations
Scholar articles
PS Sachdev, H Brodaty, S Reppermund, NA Kochan… - International psychogeriatrics, 2010