Authors
Saffiatou Darboe, Uduak Okomo, Abdul-Khalie Muhammad, Buntung Ceesay, Mamadou Jallow, Effua Usuf, Sam Tweed, Edem Akpalu, Brenda Kwambana-Adams, Samuel Kariuki, Martin Antonio, Richard S Bradbury, Karen Forrest, Thushan I de Silva, Bolarinde Joseph Lawal, Davis Nwakanma, Ousman Secka, Anna Roca
Publication date
2019/9/5
Journal
Clinical Infectious Diseases
Volume
69
Issue
Supplement_2
Pages
S105-S113
Publisher
Oxford University Press
Description
Background. Invasive bacterial diseases cause significant disease and death in sub-Saharan Africa. Several are vaccine preventable, although the impact of new vaccines and vaccine policies on disease patterns in these communities is poorly understood owing to limited surveillance data.
Methods. We conducted a hospital-based surveillance of invasive bacterial diseases in The Gambia where blood and cerebrospinal fluid (CSF) samples of hospitalized participants were processed. Three surveillance periods were defined in relation to the introduction of pneumococcal conjugate vaccines (PCVs), before (2005- 2009), during (2010–2011) and after (2012–2015) PCV introduction. We determined the prevalences of commonly isolated bacteria and compared them between the different surveillance periods.
Results. A total of 14 715 blood and …
Scholar articles
S Darboe, U Okomo, AK Muhammad, B Ceesay… - Clinical Infectious Diseases, 2019