Authors
Borja Ibanez, Anthony H Aletras, Andrew E Arai, Hakan Arheden, Jeroen Bax, Colin Berry, Chiara Bucciarelli-Ducci, Pierre Croisille, Erica Dall'Armellina, Rohan Dharmakumar, Ingo Eitel, Rodrigo Fernández-Jiménez, Matthias G Friedrich, David García-Dorado, Derek J Hausenloy, Raymond J Kim, Sebastian Kozerke, Christopher M Kramer, Michael Salerno, Javier Sánchez-González, Javier Sanz, Valentin Fuster
Publication date
2019/7/16
Source
Journal of the American College of Cardiology
Volume
74
Issue
2
Pages
238-256
Publisher
American College of Cardiology Foundation
Description
After a reperfused myocardial infarction (MI), dynamic tissue changes occur (edema, inflammation, microvascular obstruction, hemorrhage, cardiomyocyte necrosis, and ultimately replacement by fibrosis). The extension and magnitude of these changes contribute to long-term prognosis after MI. Cardiac magnetic resonance (CMR) is the gold-standard technique for noninvasive myocardial tissue characterization. CMR is also the preferred methodology for the identification of potential benefits associated with new cardioprotective strategies both in experimental and clinical trials. However, there is a wide heterogeneity in CMR methodologies used in experimental and clinical trials, including time of post-MI scan, acquisition protocols, and, more importantly, selection of endpoints. There is a need for standardization of these methodologies to improve the translation into a real clinical benefit. The main objective of this …
Scholar articles
B Ibanez, AH Aletras, AE Arai, H Arheden, J Bax… - Journal of the American College of Cardiology, 2019