Authors
Edwin Wu, Jose T Ortiz, Paula Tejedor, Daniel C Lee, Chiara Bucciarelli-Ducci, Preeti Kansal, James C Carr, Thomas A Holly, Donald Lloyd-Jones, Francis J Klocke, Robert O Bonow
Publication date
2008/6/1
Journal
Heart
Volume
94
Issue
6
Pages
730-736
Publisher
BMJ Publishing Group Ltd
Description
Objectives
Ejection fraction (EF) and end-systolic volume index (ESVI) are established predictors of outcomes following ST-segment elevation myocardial infarction (STEMI). We sought to assess the relative impact of infarct size, EF and ESVI on clinical outcomes and left ventricular (LV) remodelling.
Design
Prospective cohort study.
Setting
Academic hospital in Chicago, USA.
Patients
122 patients with STEMI following acute percutaneous reperfusion.
Main outcome measures
Death, recurrent myocardial infarction (MI) and heart failure.
Methods
Cardiac magnetic resonance imaging was obtained within 1 week following STEMI in 122 subjects. ESVI, EF and infarct size were tested for the association with outcomes over 2 years in 113 subjects, and a repeat study was obtained 4 months later to assess LV remodelling in 91 subjects.
Results
Acute infarct size correlated linearly with the initial ESVI (r = 0.69, p<0.001), end …
Total citations
Scholar articles
E Wu, JT Ortiz, P Tejedor, DC Lee, C Bucciarelli-Ducci… - Heart, 2008