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This paper presents a branch-and-price algorithm for the time-dependent vehicle routing problem with time windows (TDVRPTW). We capture road congestion by considering time-dependent travel times, i.e., depending on the departure time to a customer, a different travel time is incurred. We consider the variant of the TDVRPTW where the objective is to minimize total route duration and denote this variant the duration minimizing TDVRPTW (DM-TDVRPTW). Because of time dependency, vehicles' dispatch times at the depot are crucial as road congestion might be avoided. Because of its complexity, all known solution methods to the DM-TDVRPTW are based on (meta-)heuristics. The decomposition of an arc-based formulation leads to a set-partitioning problem as the master problem, and a time-dependent shortest path problem with resource constraints as the pricing problem. The master problem is solved by …