Authors
Janie F Shelton, Estella M Geraghty, Daniel J Tancredi, Lora D Delwiche, Rebecca J Schmidt, Beate Ritz, Robin L Hansen, Irva Hertz-Picciotto
Publication date
2014/10
Journal
Environmental health perspectives
Volume
122
Issue
10
Pages
1103-1109
Publisher
NLM-Export
Description
Background: Gestational exposure to several common agricultural pesticides can induce developmental neurotoxicity in humans, and has been associated with developmental delay and autism.
Objectives: We evaluated whether residential proximity to agricultural pesticides during pregnancy is associated with autism spectrum disorders (ASD) or developmental delay (DD) in the Childhood Autism Risks from Genetics and Environment (CHARGE) study.
Methods: The CHARGE study is a population-based case–control study of ASD, DD, and typical development. For 970 participants, commercial pesticide application data from the California Pesticide Use Report (1997–2008) were linked to the addresses during pregnancy. Pounds of active ingredient applied for organophophates, organochlorines, pyrethroids, and carbamates were aggregated within 1.25-km, 1.5-km, and 1.75-km buffer distances from the home …
Scholar articles
JF Shelton, EM Geraghty, DJ Tancredi, LD Delwiche… - Environmental health perspectives, 2014