Authors
Mark Sudlow, Richard Thomson, Barnaby Thwaites, Helen Rodgers, Rose Anne Kenny
Publication date
1998/10/10
Journal
The Lancet
Volume
352
Issue
9135
Pages
1167-1171
Publisher
Elsevier
Description
Background
Anticoagulants are effective in the prevention of stroke in atrial fibrillation and flutter (AF). We aimed to find out the prevalence of AF in the UK and to estimate the proportion of patients with AF who might benefit from anticoagulation.
Methods
We screened with electrocardiography a random sample of 4843 people from the community aged 65 years and older for AF. Participants with AF had further investigations to identify risk factors for stroke and contraindications to anticoagulants. We used three sets of criteria to assess risk and elibility for anticoagulation.
Findings
228 (4·7%) participants had AF. According to analyses derived from risk stratifications based on the Stroke Prevention in Atrial Fibrillation (SPAF) study 61% of these patients would have benefited from anticoagulation, 49% according to pooled analysis of trial results, and 41% according to the inclusion criteria for the SPAF 3 study …
Total citations
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