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The constrained one‐step spectral CT Image Reconstruction method (cOSSCIR) has been developed to estimate basis material maps directly from spectral CT data using a model of the polyenergetic x‐ray transmissions and incorporating convex constraints into the inversion problem. This ‘one‐step’ approach has been shown to stabilize the inversion in the case of photon‐counting CT, and may provide similar benefits to dual‐kV systems that utilize integrating detectors. Since the approach does not require the same rays be acquired for every spectral measurement, cOSSCIR can apply to dual energy protocols and systems used clinically, such as fast and slow kV switching systems and dual source scanning.

The purpose of this study is to investigate the use of cOSSCIR applied to dual‐kV data, using both registered and unregistered spectral acquisitions, specifically slow and fast kV …