Authors
Mosaad SM Alla, Mohamed I Hegab, Nageh A Abo Taleb, Sherifa M Hasabelnaby, A Goudah
Publication date
2010/4/1
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume
45
Issue
4
Pages
1267-1277
Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES
Description
Some new 1,3,4-triazolo-, 1,3,4-oxadiazolo-, 1,3,4-thiadiazol-, and pyrazolo-3,4-dimethylphenyl-1(2H)-oxo-phthalazine derivatives were synthesized and identified by IR, 1H NMR, MS and elemental analysis. Most of the newly synthesized products were tested for their anti-inflammatory activities. Among them, compounds 11, 17b, 20, 21 and 22 are active compare to the activity of indomethacin®.
Total citations
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