Authors
Saef Izzy, Patrick M Chen, Zabreen Tahir, Rachel Grashow, Farid Radmanesh, David J Cote, Taha Yahya, Amar Dhand, Herman Taylor, Shirley L Shih, Omar Albastaki, Craig Rovito, Samuel B Snider, Michael Whalen, David M Nathan, Karen K Miller, Frank E Speizer, Aaron Baggish, Marc G Weisskopf, Ross Zafonte
Publication date
2022/4/1
Journal
JAMA network open
Volume
5
Issue
4
Pages
e229478-e229478
Publisher
American Medical Association
Description
Importance
Increased risk of neurological and psychiatric conditions after traumatic brain injury (TBI) is well-defined. However, cardiovascular and endocrine comorbidity risk after TBI in individuals without these comorbidities and associations with post-TBI mortality have received little attention.
Objective
To assess the incidence of cardiovascular, endocrine, neurological, and psychiatric comorbidities in patients with mild TBI (mTBI) or moderate to severe TBI (msTBI) and analyze associations between post-TBI comorbidities and mortality.
Design, Setting, and Participants
This prospective longitudinal cohort study used hospital-based patient registry data from a tertiary academic medical center to select patients without any prior clinical comorbidities who experienced TBI from 2000 to 2015. Using the same data registry, individuals without head injuries, the unexposed group, and without target comorbidities were …
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Scholar articles
S Izzy, PM Chen, Z Tahir, R Grashow, F Radmanesh… - JAMA network open, 2022