Authors
Cyrus Martin, Yi Zhang
Publication date
2005/11/1
Journal
Nature Reviews Molecular Cell Biology
Volume
6
Issue
11
Pages
838-849
Publisher
Nature Publishing Group
Description
Covalent modifications of histone tails have fundamental roles in chromatin structure and function. One such modification, lysine methylation, has important functions in many biological processes that include heterochromatin formation, X-chromosome inactivation and transcriptional regulation. Here, we summarize recent advances in our understanding of how lysine methylation functions in these diverse biological processes, and raise questions that need to be addressed in the future.
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Scholar articles
C Martin, Y Zhang - Nature reviews Molecular cell biology, 2005