Authors
Yuichiro Yada, Takeshi Mita, Ryohei Kanzaki, Douglas J Bakkum, Hirokazu Takahashi
Publication date
2015/4/22
Conference
2015 7th International IEEE/EMBS Conference on Neural Engineering (NER)
Pages
344-347
Publisher
IEEE
Description
Synchrony in a neuronal network is not just a spontaneous event but rather a representation of inner information. In this point of view, the variety of synchrony patterns is considered to be related to inner capacity of the network. However, evaluating and comparing the variety of synchrony patterns, especially between different samples or different times, is difficult. In this paper, we proposed to identify the variety of synchrony based on Bayesian model selection. Hypothesizing that globally synchronized activity consists of partial synchrony, we attempted to identify reproducible-spatial pattern bases in spontaneous bursting activities of dissociated cortical cultures using Bayesian non-negative matrix factorization. Neuronal activity was recorded with high-density CMOS electrode arrays. Bayesian treatment provides evidence for selection of the number of bases based on marginal likelihood. We compared model …
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Scholar articles
Y Yada, T Mita, R Kanzaki, DJ Bakkum, H Takahashi - 2015 7th International IEEE/EMBS Conference on …, 2015