Authors
David T Felson, Josef S Smolen, George Wells, Bin Zhang, Lilian HD Van Tuyl, Julia Funovits, Daniel Aletaha, Cornelia F Allaart, Joan Bathon, Stefano Bombardieri, Peter Brooks, Andrew Brown, Marco Matucci‐Cerinic, Hyon Choi, Bernard Combe, Maarten De Wit, Maxime Dougados, Paul Emery, Daniel Furst, Juan Gomez‐Reino, Gillian Hawker, Edward Keystone, Dinesh Khanna, John Kirwan, Tore K Kvien, Robert Landewé, Joachim Listing, Kaleb Michaud, Emilio Martin‐Mola, Pamela Montie, Theodore Pincus, Pamela Richards, Jeffrey N Siegel, Lee S Simon, Tuulikki Sokka, Vibeke Strand, Peter Tugwell, Alan Tyndall, Desirée Van Der Heijde, Suzan Verstappen, Barbara White, Frederick Wolfe, Angela Zink, Maarten Boers
Publication date
2011/3
Journal
Arthritis & Rheumatism
Volume
63
Issue
3
Pages
573-586
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Description
Objective
Remission in rheumatoid arthritis (RA) is an increasingly attainable goal, but there is no widely used definition of remission that is stringent but achievable and could be applied uniformly as an outcome measure in clinical trials. This work was undertaken to develop such a definition.
Methods
A committee consisting of members of the American College of Rheumatology, the European League Against Rheumatism, and the Outcome Measures in Rheumatology Initiative met to guide the process and review prespecified analyses from RA clinical trials. The committee requested a stringent definition (little, if any, active disease) and decided to use core set measures including, as a minimum, joint counts and levels of an acute‐phase reactant to define remission. Members were surveyed to select the level of each core set measure that would be consistent with remission. Candidate definitions of remission …
Total citations
Scholar articles
DT Felson, JS Smolen, G Wells, B Zhang… - Arthritis & Rheumatism, 2011
DT Felson, JS Smolen, G Wells, B Zhang, LH van Tuyl… - Arthritis Rheum, 2011