Authors
Keith Siew, Vaksha Patel, Jasminka Zimmermann, Michael Vaughan, Christopher Cheshire, Angela Kubik, Rebecca Finch, Zhongwang Li, Selin Altinok, Willian De Silvera, Samuel Rodriques, Elizabeth Blaber, Jonathan Schisler, Jonathan Galazka, Muratani Masafumi, Afshin Beheshti, Stephen Walsh, Michael Lean, Roy Taylor, Naveed Sattar, Alasdair Mcintosh, Wilma Leslie, Louise McCombie, Naomi Brosnahan, George Thom, Alison Barnes, Keaton Irvine, Sarah Cook, Sara Hatem, Sean Scully, Hywel T Evans, Ian Farr, Chris Orton, David V Ford, Aziz Sheikh, Jennifer K Quint, David Ferenbach, Lowri Allen, Georgina Mortimer, Rana Fareed, Claire Williams, Steve Bain, Colin Dayan, Diane Fraser, William Hagopian, Richard Oram, Kathleen Gillespie, Omid Sadeghi-Alavijeh, Melanie Chan, Shabbir Moochhala, Sarah Howles, Daniel Gale, Detlef Böckenhauer, Rachel Jennings, Syed Murtuza Baker, Peyman Zarrineh, Ali Al-Banaki, Aoibheann Mullan, Maria Alexandra Goncalves, Neil Hanley, Caroline Watson, Sophia Apostolidou, Usha Menon, Jamie Blundell, Claire Shovlin, Maria Bernabeu-Herrero, Kinshuk Jain, Michaela Aldred, Adrianna Bielowka, Ian Mackay, Patricia Chaves Guerrero, Stefan Marciniak, Michela Noseda, Dilipkumar Patel, Antonia Ho, Richard Orton, Rachel Tayler, Patawee Asamaphan, Vanessa Herder, Chris Davis, Lily Tong, Katherine Smollett, Louisa Pollock, Clair Evans, Jim McMenamin, Kirsty Roy, Kimberly Marsh, Titus Divala, Matt Holden, Michael Lockhart, Samantha Shepherd, Celia Jackson, Rory Gunson, Alasdair MacLean, Paul Henderson, Meera Chand, Michael Levin, Massimo Palmarini, David Robertson, Ana da Silva Filipe, Brian Willett, Judith Breuer, Malcolm Semple, David Turner, Kenneth Baillie, Emma Thomson, Elsie Horne, William Hulme, Ruth Keogh, Tom Palmer, Elizabeth Williamson, Edward Parker, Venexia Walker, OpenSAFELYCollaborative, Ben Goldacre, Miguel Hernán, Jonathan Sterne, Jeremy Schofield, Simon Abrams, Yasir Alhamdi, Keirah Bartlett, Steve Hall, Guozheng Wang, Nicholas Casewell, Cheng-Hock Toh, Ashkan Dashtban, Mehrdad Mizani, Laura Pasea, Spiros Denaxas, Richard Corbett, Jilbilly Mamza, He Gao, Tamsin Morris, Harry Hemingway, Amitava Banerjee, Zahra Raisi-Estabragh, Maddalena Ardissino, Andrew Bard, Liliana Szabo, Ahmed Salih, Celeste McCracken, Esmeralda Ruiz, Andre Altman, Charalambos Antoniades, Stefan Neubauer, Karim Lekadir, Steffen Petersen, Jennifer Lees, Jamie Crowther, Peter Hanlon
Publication date
2023/7/7
Journal
QJM: An International Journal of Medicine
Pages
hcad072
Publisher
Oxford University Press
Description
Background
DiRECT was a 2-year randomised controlled trial of dietary weight management: remission of T2D (HbA1c< 48mmol/mol without medication) was achieved by 46% at year-1, 36% at-year-2, and by 70-80% of those losing> 10kg.
Methods
For the DiRECT-Extension, intervention participants were offered low-intensity nurse or dietitian support, up to 5 years. NHS data were collected annually from all originally randomised participants.
Scholar articles
K Siew, V Patel, J Zimmermann, M Vaughan… - QJM: An International Journal of Medicine, 2023