Authors
İpek Süntar, Esra Küpeli Akkol, Fatma Sezer Şenol, Hikmet Keles, Ilkay Erdogan Orhan
Publication date
2011/4/26
Journal
Journal of ethnopharmacology
Volume
135
Issue
1
Pages
71-77
Publisher
Elsevier
Description
ETHNOPHARMACOLOGICAL RELEVANCE
Salvia L. species are widely used against wounds and skin infections in Turkish folk medicine.
AIM OF THE STUDY
The aim of the present study is to evaluate wound healing activity of the ethanol (EtOH) extracts of Salvia cryptantha and Salvia cyanescens.
MATERIALS AND METHODS
For the assessment of wound healing activity linear incision and circular excision wound models were employed on rats and mice. The wound healing effect was comparatively evaluated with the standard skin ointment Madecassol®. Inhibition of tyrosinase, a key enzyme in skin aging, was achieved using ELISA microplate reader. Antioxidant activity was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and superoxide radical scavenger effect, ferrous ion-chelating ability, and ferric-reducing antioxidant power (FRAP) tests.
RESULTS AND CONCLUSIONS
The EtOH extract of Salvia …
Scholar articles
İ Süntar, EK Akkol, FS Şenol, H Keles, IE Orhan - Journal of ethnopharmacology, 2011