Authors
Ipek Süntar, Ufuk Koca, Hikmet Keleş, Esra Küpeli Akkol
Publication date
2011
Journal
Evidence‐Based Complementary and Alternative Medicine
Volume
2011
Issue
1
Pages
816156
Publisher
Hindawi Publishing Corporation
Description
Young shoots of Rubus species have been used for healing of wounds, infected insect bites and pimples in folk medicine for ages. In order to evaluate the wound healing activity of Rubus sanctus, four different extracts were prepared from the whole aerial parts of the plant by using n‐hexane, chloroform, ethyl acetate and methanol, respectively. Incision wound healing model by using tensiometer on rats and excision model on mice were employed to assess the activity. Remarkable wound healing activity was observed with the ointment formulation of the methanol extract at 1% concentration on the mentioned models. The results of histopathological examination also supported the outcome of both incision and excision wound models. The wound healing effect was comparatively evaluated with a reference ointment Madecassol. The experimental data confirmed the ethnobotanical usage of R. sanctus.
Scholar articles
I Süntar, U Koca, H Keleş, EK Akkol - Evidence‐Based Complementary and Alternative …, 2011
I Süntar, U Koca, H Keleş, EK Akkol - Evidence Based Complementary and …, 2009
I Suntar, U Koca, H Keles, EKAWH Activity - Article ID
S Ipek, K Ufuk, K Hikmet, A Esra Küpeli - Evidence-Based Complementary and Alternative …